PRISM: Patient Experiences With PET Imaging in Prostate Cancer (PRISM)

  • STATUS
    Recruiting
  • End date
    Jul 17, 2028
  • participants needed
    300
  • sponsor
    Yale University
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Updated on 17 April 2025
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Summary

The purpose of this study is to examine patient experiences, health-related quality of life, and decision-making associated with PET imaging for prostate cancer. In particular, Prostate Specific Membrane Antigen (PSMA) PET, a new and more sensitive form of imaging that can help identify metastatic cancer earlier and more reliably.

Description

The primary objective is to measure health related quality of life among patients with prostate cancer who are undergoing prostate specific membrane positron emission tomography (PSMA-PET) imaging. This will be assessed in four domains: cancer related anxiety, decisional conflict, health related quality of life (physical functioning) and health preferences.

The secondary objective is to conduct longitudinal in-depth qualitative interviews to better explore patient experiences and perspectives on PET imaging.

Study Design Investigators will conduct a longitudinal explanatory sequential mixed methods study consisting of two phases. In the first phase, serial quantitative psychological (anxiety, uncertainty) and HRQoL survey data from patients undergoing PET imaging in routine clinical care will be collected. In the second phase, a subset of patients from phase 1 who have completed initial surveys will be recruited and conduct longitudinal in-depth qualitative interviews to better explore patient experiences and perspectives on PET imaging.

Patient clinical and sociodemographic data will be collected through automated extraction from the medical record (EPIC) into the REDcap database through collaboration with JDAT. For fields that are not populated via automated methods we will manually enter information via abstraction of the patient's medical record (EPIC).

Details
Condition Prostate Cancer
Age 18years or above
Clinical Study IdentifierNCT06523777
SponsorYale University
Last Modified on17 April 2025

Eligibility

 Yes No Not Sure

Inclusion Criteria

Documented diagnosis of prostate cancer
Scheduled for their FIRST PSMA PET scan for prostate cancer
English-speaking
Willing and able to complete 4 surveys electronically or on paper at 3 timepoints (within 1 month after PET scan, 3-6 months, 12 months)
Able to use mobile device (smartphone or tablet) or computer with web access to complete study surveys or able to complete paper surveys

Exclusion Criteria

Lack of access to a mobile device (smartphone or tablet) or computer with web access or unable to receive surveys by mail
Unable to give consent and be enrolled
PET scan is being conducted within a clinical trial
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