A Study of the Correlation Between Portal Vein Thrombosis and Prognosis of Liver Transplantation

  • STATUS
    Recruiting
  • End date
    Dec 31, 2025
  • participants needed
    700
  • sponsor
    Ru-zhou Cai
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Updated on 23 July 2024
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Summary

The goal of this observational study is to investigate the correlation between portal vein thrombosis (PVT) and the prognosis of liver transplantation. The main questions it aims to address are:

What is the prevalence of PVT? What are the risk factors associated with PVT? What is the prognostic impact of preoperative PVT on liver transplantation?

Participants are divided into two groups: the PVT group and the non-PVT group. The investigators will comparatively analyze the data of both groups, estimate the prevalence and risk factors of PVT, construct a predictive model for PVT that is applicable in clinical settings, and clarify the prognostic effects of PVT.

Description

The investigators aim to investigate the prevalence and risk factors of PVT, to develop a novel grading or rating system for PVT, and to explore the prognostic impact of preoperative PVT in liver transplantation.

The investigators will:

Recruit patients according to the inclusion/exclusion criteria and obtain signed informed consents. They will collect demographic and laboratory characteristics and classify patients into the PVT group and the non-PVT group based on preoperative ultrasound and/or computed tomography.

Collect patients' perioperative medical imaging, surgical procedures, pathology reports, postoperative treatments, follow-up data, and clinical endpoints.

Comparatively analyze the data of the PVT and non-PVT groups, estimate the prevalence and risk factors of PVT, construct a predictive model for PVT that is applicable in clinical settings, clarify the prognostic effects of PVT, and propose a grading/rating system for PVT.

Details
Condition Portal Vein Thrombosis
Age 18years or above
Treatment Observation
Clinical Study IdentifierNCT06513780
SponsorRu-zhou Cai
Last Modified on23 July 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Liver transplantation recipients
Aged 18 years or older

Exclusion Criteria

Retransplantation
Multi-organ transplantation
Portal vein tumor thrombus
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