This study is currently not recruiting participants.

Study on Optimal Treatment Strategy for Elderly Patients With High-risk Complex Aortic Valve Disease

  • STATUS
    Not Recruiting
  • participants needed
    540
  • sponsor
    Yongjian Wu
Updated on 14 February 2024

Summary

Aortic valve disease (AVD) is the most common and age-related mortality in elderly patients with valvular heart disease (VHD). Although transcatheter aortic valve replacement (TAVR) has been recommended at a higher level in foreign guidelines, there are still many high-risk and severe elderly patients with VHD who have not received effective treatment because of many complications and untimely medical treatment. Different from Europe and the United States, the majority of patients with bicuspid aortic valve are in China, and the calcification is more serious. The current clinical evaluation system and treatment guidelines can not be effectively applied to the high-risk and complex elderly patients. Therefore, the investigators should train and set up a valvular heart disease team, explore the technical difficulties of TAVR treatment in such patients, establish emergency TAVR operation mechanism, build a clinical evaluation system for high-risk and complex elderly patients with aortic valve disease in China, evaluate the curative effect periodically and further optimize the treatment strategy, so as to improve the quality of life and the meaning of life cycle of elderly patients with VHD in China Great significance.

Details
Condition Aortic Valve Disease
Age 75years or above
Clinical Study IdentifierNCT05044377
SponsorYongjian Wu
Last Modified on14 February 2024

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