This study is currently not recruiting participants.

Breaking Sitting With High-intensity Interval Training for Brain Health (HIIT2SITLess)

  • STATUS
    Not Recruiting
  • participants needed
    54
  • sponsor
    University of Illinois at Urbana-Champaign
Updated on 6 February 2024
Accepts healthy volunteers

Summary

This trial will examine whether interrupting 3.5 hours of sitting every 30 min with 6 min high intensity interval training (HIIT) breaks compared to light intensity interval training (LIIT) will improve brain health in cognitively normal older adults. This trial will test the feasibility of HIIT breaks to sitting. It will also address several important but unanswered questions: (1) Does interrupting sitting with short HIIT breaks improve frontoparietal function? (2) Can interrupting sitting with HIIT breaks improve cognitive functions?

Description

The investigators are conducting an acute, single site randomized crossover trial testing two conditions lasting 3.5 hours each with a one to four-weeks washout period: (1) Interrupting sitting with 6 min of high-intensity interval training (HIIT) every 30 min, and (2) interrupting sitting with 6-min light-intensity interval training (LIIT) every 30 min. Investigators will administer the conditions in a counterbalanced order to 54 older adults (60-75 years). Brain function will be assessed using event-related brain potentials and measures of functional connectivity derived from electroencephalography. Cognitive functions will be assessed using a modified Eriksen flanker task and an antisaccade task. Investigators will measure episodic memory using a mnemonic discrimination task.

Details
Condition Aging
Age 60years - 75years
Treatment High-Intensity Interval Training (HIIT) Breaks to Sitting, Light-Intensity Interval Training (LIIT) Breaks to Sitting
Clinical Study IdentifierNCT06243016
SponsorUniversity of Illinois at Urbana-Champaign
Last Modified on6 February 2024

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