MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

  • STATUS
    Recruiting
  • participants needed
    20
  • sponsor
    Shengjing Hospital
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Updated on 25 July 2023
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Summary

In spinal cord tumors requiring surgical intervention, the resection difficulty is determined by two significant factors: tumor stiffness and adhesion to surrounding tissue.

The stiffness of the tumor dictates the complexity of removal, while strong adhesion presents additional challenges during the surgical procedure.

This clinical trial aims to assess the clinical utility of magnetic resonance elastography (MRE), in evaluating the stiffness and adhesion of spinal cord tumors and guiding surgical planning to selecting the most appropriate surgical approach for patients with spinal cord tumors.

Description

Spinal cord tumors are a common condition in neurosurgery, including neurofibroma, spinal meningioma, ependymoma, glioma, spinal lipoma, and so on.

Magnetic resonance imaging (MRI) plays a crucial role in the preoperative evaluation and planning of spinal cord tumor surgery. It provides detailed information about the tumor's location, size, and relationship to adjacent structures.

However, routine MRI may not always provide sufficient information about the tumor's stiffness or adhesion, which can impact surgical planning and postoperative outcomes. Magnetic resonance elastography and slip interface imaging can help measure the mechanical properties of tissues, including their stiffness or adhesion.

By combining the above methods, surgeons can identify areas of potential tumor adherence or invasion into surrounding structures, allowing for more precise surgical resection and minimizing the risk of damage to critical neural tissue.

Details
Condition Spinal Cord Tumors
Age 18years - 80years
Treatment Magnetic Resonance Elastography, Assessment and Recording
Clinical Study IdentifierNCT05957679
SponsorShengjing Hospital
Last Modified on25 July 2023

Eligibility

 Yes No Not Sure

Inclusion Criteria

All patients undergoing brain tumor resection surgery at Shengjing Hospital affiliated with China Medical University are eligible for inclusion in the study cohort

Exclusion Criteria

Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who cannot remove dentures, insulin pumps, or contraceptive rings)
Pregnant women in the first trimester (within three months)
Patients with severe claustrophobia or anxiety
Patients with severe fever
Patients who can not tolerate MRE
Patients with vascular malformations and aneurysms
Patients who do not sign an informed consent
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