Neuronavigation rTMS to Improve Depressive Episodes of Bipolar Disorder in Adolescent

  • STATUS
    Recruiting
  • participants needed
    50
  • sponsor
    First Affiliated Hospital of Zhejiang University
Send
Updated on 5 July 2023
See if I qualify

Summary

The purpose of this study is to explore a new stimulation target and protocol for the treatment of depressive episode in adolescents with bipolar disorder through the repetitive transcranial magnetic stimulation(rTMS) under neuronavigation, and verify whether there is abnormal functional connectivity between the emotion-related brain area orbital frontal lobe (OFC) and the primary visual cortex(V1) during the depressive episode, which will contribute to further understand the relevant neural pathway and mechanism.

Details
Condition Bipolar Disorder
Age 14years - 28years
Treatment repetitive transcranial magnetic stimulation, Sham Repetitive Transcranial magnetic stimulation
Clinical Study IdentifierNCT05929183
SponsorFirst Affiliated Hospital of Zhejiang University
Last Modified on5 July 2023

Eligibility

 Yes No Not Sure

Inclusion Criteria

Age 14-28 years old, regardless of gender
Meet DSM-V diagnostic criteria for bipolar depressive episodes
Young Mania Rating Scale (YMRS) ≤ 6 points
MARDS:12-30 points
Han nationality, right-handed
More than 9 years of education

Exclusion Criteria

History of severe somatic or brain organic diseases and craniocerebral trauma
Abnormal brain structure or any MRI contraindications were found by magnetic resonance examination
Those who do not cooperate or cannot effectively complete the experiment
Drug, alcohol or other psychoactive substance abusers
Pregnant, lactating or planned pregnancy
Severe suicidal ideation and behavior
ECT or rTMS treatment was performed within six months
Clear my responses
Read more

How to participate?

Step 1 Connect with a study center
Message sent successfully.
We have submitted the information you provided to the research team at the location you chose. For your records, we have sent a copy of the message to your email address.
If you would like to be informed of other studies that may be of interest to you, you may sign up for Patient Notification Service.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

First name*
Last name*
Email*
Phone number*
Other language

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.