Renal Nerve Denervation(RDN) and Renal Function

  • STATUS
    Recruiting
  • participants needed
    50
  • sponsor
    Zhengrong Huang
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Updated on 21 December 2022
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Summary

Current studies have found the efficacy of RDN in the treatment of hypertension, however, the safety of RDN in renal function is still lacking. Therefore, the investigators are aimed to study the effect of RDN on renal function.

Description


Details
Condition Effects of RDN on Renal Function
Age 18years - 75years
Clinical Study IdentifierNCT05612906
SponsorZhengrong Huang
Last Modified on21 December 2022

Eligibility

 Yes No Not Sure

Inclusion Criteria

18<age≤75 years; 2.clinic blood pressure ≥ 140/90 mmHg or 24-hour ambulatory blood
pressure monitoring average blood pressure ≥ 135/85 mmHg after taking 3 or more
antihypertensive drugs for more than 4 weeks; 3.essential hypertension, renal parenchymal
hypertension, or hypertension patients who are willing to receive RDN ; 4.who signed
informed consent and were approved by the Ethics Committee of the First Affiliated Hospital
of Xiamen University

Exclusion Criteria

pregnant women or lactating patients
identified secondary hypertension or Pseudo hypertension
whose renal arteries were unsuitable for ablation
obvious bleeding tendency and blood system diseases
malignant tumors or end-stage diseases; ⑥Severe peripheral
vascular disease, abdominal aortic aneurysm; ⑦A history of the
acute coronary syndrome within two weeks; ⑧acute or severe
systemic infection; ⑨drug or alcohol dependence or refusal to sign
informed consent
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