Effect of Cannabis Use on Synaptic Density in Older Adults

  • STATUS
    Recruiting
  • participants needed
    24
  • sponsor
    Yale University
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Updated on 20 July 2022
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Accepts healthy volunteers

Summary

The aim of the study is to examine the effect of cannabis use on brain synaptic density among older adults using [11C]UCB-J PET imaging.

Details
Condition Cannabis Use
Age 50years or above
Treatment [11C]UCB-J PET
Clinical Study IdentifierNCT05465538
SponsorYale University
Last Modified on20 July 2022

Eligibility

 Yes No Not Sure

Inclusion Criteria

Able to provide informed consent
Male or female, aged ≥50 years
No history of significant medical or neurological disease
If woman of childbearing potential, must agree to use an acceptable method of birth control, as determined by the principal investigator, for the duration of the study and up to one month after completion of PET scans

Exclusion Criteria

Women with a positive pregnancy test or women who are lactating
Have had exposure to ionizing radiation that in combination with the study tracer would result in a cumulative exposure that exceeds recommended exposure limits
History of a bleeding disorder or are currently taking anticoagulants
Subjects who have donated blood within 8 weeks of the present study
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