Comparison of Glucose Values and Variability Between TOUJEO and TRESIBA During Continuous Glucose Monitoring in Type 1 Diabetes Patients

  • STATUS
    Recruiting
  • participants needed
    338
  • sponsor
    Sanofi
Updated on 21 July 2021
glycosylated hemoglobin
hemoglobin a1c
continuous glucose monitoring
type 1 diabetes mellitus
tresiba
diabetes
insulin

Summary

Primary Objective:

To demonstrate the noninferiority of insulin glargine 300 U/mL in comparison to insulin degludec 100 U/mL on glycemic control and variability in participants with diabetes mellitus

Secondary Objective:

To evaluate the glycemic control and variability parameters in each treatment group at Week 12 using Continuous Glucose Monitoring (CGM)

To evaluate the safety of insulin glargine 300 U/mL in comparison to insulin degludec 100 U/mL

Description

The duration of the study per participant will be around 18 weeks :1 or 2 weeks of screening followed by a 4-week run-in period, a 12-week treatment period and a 2 to 4 days follow-up period

Details
Condition Diabetes Mellitus, Diabetes Mellitus Types I and II, diabetes prevention, diabetes (pediatric), Insulin dependent diabetes mellitus, diabetes mellitus, type 1, diabetes (pediatric), Diabetes Mellitus Types I and II, diabetes prevention, diabetes mellitus, type 1, type 1 diabetes mellitus
Age 18years - 70years
Treatment Insulin glargine, 300 U/ml, Insulin degludec, 100U/ml, Background therapy: Rapid acting insulin analogs
Clinical Study IdentifierNCT04075513
SponsorSanofi
Last Modified on21 July 2021

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