Inguinal Hernia and Arterial Disease

  • STATUS
    Recruiting
  • participants needed
    100
  • sponsor
    University of Catanzaro
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Updated on 5 August 2020
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stenosis
arterial disease
peripheral artery disease
duplex scan
matrix
extracellular matrix alterations

Summary

Inguinal hernias are associated with problems related to the venous system by the linking to extracellular matrix alterations (ECM). On the other hand, arterial diseases (arterial aneurysms, carotid, stenosis, peripheral artery disease) are widespread in the general population and may share others pathological pathways related to ECM impairment. Aim to this study is to evaluate the prevalence of arterial diseases in patients with inguinal hernia.

Description

Previous studies showed the correlation between inguinal hernias and venous disease. The common pathophysiological pathway between these clinical conditions is linked to extracellular matrix (ECM) alterations. Arterial diseases, mainly represented by carotid stenosis, peripheral artery disease and arterial aneurysms, are widespread in western population and are responsible of high rates of morbidity and mortality. These diseases are also related to some ECM alterations.

Aim of this cross-sectional study is to evaluate the prevalence of arterial disease among patients with inguinal hernias. The primary endpoint of this study is to provide new epidemiological evidences on this association that may help physicians in novel preventive strategies. The study will consider the inclusion of consecutive patients assessed for inguinal hernia over 1 year period in order to study the prevalence of concomitant arterial disease, by means of office visit, echo duplex scan of the aorta and its main branches, carotid arteries and lower limb arteries.

Details
Condition INGUINAL HERNIA, Arterial Disease
Age 18years - 100years
Treatment In-office vascular visit, Echo duplex scan of arterial system
Clinical Study IdentifierNCT04428138
SponsorUniversity of Catanzaro
Last Modified on5 August 2020

Eligibility

 Yes No Not Sure

Inclusion Criteria

patients with inguinal hernia

Exclusion Criteria

patients with malignancies
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