Is SPGB Have an Effect on ICP and Oxygenation of Cerebral Venous Outflow in Craniotomy for Cerebral Tumors?

  • STATUS
    Recruiting
  • participants needed
    20
  • sponsor
    Zagazig University
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Updated on 5 August 2020
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Summary

This study aims to investigate the effect of Sphenopalatine Ganglion Block on ICP and arterio- jugular venous oxygen difference (AJVDO2) and jugular bulb oxygen saturation (SjVO2). Throughout this study, the efficacy of Sphenopalatine Ganglion Block as scalp block in craniotomy operation will be assessed, and the effect of SPGB on cerebral hemostasis during craniotomy will be evaluated by monitoring of both ICP, AJVDO2 and SjVO2.

Description

This study was performed in the Neurosurgical operating room and included 20 patients allocated into two groups: the treatment group (block group) and the control group (non-block group). 10 patients enrolled in block group and 10 patients in non-block group.

Intraoperative ICP monitoring by subdural ICP monitors will be done every 20 minutes in both block and non- block groups until craniotomy has been occurred, then at the time of closure of the dura . Arterio- jugular venous oxygen difference and Jugular venous bulb oxygen saturation changes will be recorded every 20 minutes in block and non- block groups throughout time of the surgery.

Details
Condition Cerebral Tumor
Age 18years - 70years
Treatment SPGB
Clinical Study IdentifierNCT04434651
SponsorZagazig University
Last Modified on5 August 2020

Eligibility

 Yes No Not Sure

Inclusion Criteria

Patients who prepared for a neurosurgical intervention for elective supratentorial tumor removal
ASA 1 and 2
Age above 18 years and below 70 years
Fully conscious patients

Exclusion Criteria

Patients with cardiovascular including hypertensive patients or respiratory diseases
Pregnancy
Patient refusal
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