Mesenchymal Stromal Cell Therapy for Severe Covid-19 Infection

  • STATUS
    Recruiting
  • participants needed
    20
  • sponsor
    University of Liege
Send
Updated on 5 August 2020
See if I qualify
ct scan
mechanical ventilation
pneumonia
alcoholism
lidocaine
covid-19
SARS
mental illness
cell therapy
acute respiratory syndrome (sars)

Summary

The overall objective of the study is to evaluate the safety and efficacy of MSC therapy combined with best supportive care in hospitalized patients with COVID-19.

Description

This study is a monocentric prospective phase I/II clinical trial, aiming at evaluating the safety and efficacy of 3 intravenous administrations of BM-MSC in 20 patients with severe to critical COVID-19 pneumonia.

After signed informed consent, patients will receive 3 infusions of (1.5)-3.0 x106/kg BM-MSC (from the same donor) at 3-4 days interval, in addition to the standard of care for COVID-19 disease.

The trial will be open for inclusion for 2 years after initiation. Each patient will be followed for 90 days after inclusion. The total study duration will thus be 2 years and 90 days.

Details
Condition Coronavirus Infection
Age 18years - 70years
Treatment Mesenchymal stromal cells
Clinical Study IdentifierNCT04445454
SponsorUniversity of Liege
Last Modified on5 August 2020

Eligibility

 Yes No Not Sure

Inclusion Criteria

Known allergy to lidocaine
Any risk factor for transmissible infectious diseases, in particular HIV
Clear my responses
Read more

How to participate?

Step 1 Connect with a study center
Message sent successfully.
We have submitted the information you provided to the research team at the location you chose. For your records, we have sent a copy of the message to your email address.
If you would like to be informed of other studies that may be of interest to you, you may sign up for Patient Notification Service.
Sign up

Send a message

Enter your contact details to connect with study team

Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

First name*
Last name*
Email*
Phone number*
Other language

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Browse trials for

ct scan
mechanical ventilation
pneumonia
alcoholism
lidocaine
covid-19
SARS
mental illness
cell therapy
acute respiratory syndrome (sars)

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.