Corneal Biomechanics During Pregnancy

  • STATUS
    Recruiting
  • participants needed
    50
  • sponsor
    University of Zurich
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Updated on 5 August 2020
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intraocular pressure

Summary

It is known that intraocular pressure changes during pregnancy. Collagen structure changes during pregnancy to enable softening of the symphysis, whitening of the birth chanel, and, thus, ultimately to enable delivery of a child. The cornea consists of highly structured collagen fibers. Hence, it seams logically that corneal biomechanics also change during pregnancy.

Description

It is known that intraocular pressure changes during pregnancy. Collagen structure changes during pregnancy to enable softening of the symphysis, whitening of the birth chanel, and, thus, ultimately to enable delivery of a child. The cornea consists of highly structured collagen fibers. Hence, it seams logically that corneal biomechanics also change during pregnancy.

Measurement of intraocular pressure is highly dependant on corneal properties. With the Corvis ST device by Ocular Inc. it is possible to measure intraocular pressure and investigated corneal biomechanics. The aim of this study is therefore to compare corneal biomechanical properties during the third trimester with corneal biomechanical properties at 3 months after delivery.

Details
Condition Pregnancy, Pregnancy
Age 18years - 38years
Treatment Non-Contact measurement of corneal properties
Clinical Study IdentifierNCT04433689
SponsorUniversity of Zurich
Last Modified on5 August 2020

Eligibility

 Yes No Not Sure

Inclusion Criteria

females
pregnant
age 18 to 38 yo
uncomplicated singleton pregnancy

Exclusion Criteria

any history of ocular disease or surgery other than conjunctivitis, especially no history of glaucoma or corneal disease
systemic diseases, i.e. diabetes, hypertension, collagenase
current contact lens wear
before pregnancy taking any systemic or ocular medications
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