An Observational Study to Assess the Protocol for the COVID-19 Treatment in Burkina Faso

  • STATUS
    Recruiting
  • participants needed
    150
  • sponsor
    Centre Muraz
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Updated on 16 February 2024
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azithromycin
covid-19
chloroquine
hydroxychloroquine
coronavirus infection
azithormycin

Summary

This is an observational study to evaluate the effectiveness of the combinations Hydroxychloroquine + Azithromycin (HCQ-AZ) and Chloroquine + Azithromycin (CQ-AZ) in the treatment of Coronavirus (Covid-19) infection in Burkina Faso.

Description

All patients who received one of the two combinations will be included in the study and followed-up until the patient is discharged from the hospital. They will be seen daily during the period of their active clinical follow-up at the hospital. At each visit, the medical history since the last visit (including treatments taken), signs and symptoms in progress if any, will be collected. A nasopharyngeal swab will be collected on Day 0, 3, 7 and 14 and then on day 21 if he is still positive in order to assess the evolution of the viral load. However if until the end of the follow-up on D21 the test is still positive, the sampling will be continued until the patient become negative as recommended by the national standard of care for the Covid patients management in Burkina Faso.

In terms of safety, an ECG will be performed on day 0 prior to the treatment administration and this will be repeated on day 7 and day 14 and every week until it normalizes or the patient will be recommended to see a cardiologist to check the normalization of his ECG after discharge from hospital. Adverse events will be recorded including biological parameters (biochemistry and hematology) will be monitored, as well as changes in relevant laboratory parameters.

Details
Condition Coronavirus Infection
Age 18years - 99years
Clinical Study IdentifierNCT04445441
SponsorCentre Muraz
Last Modified on16 February 2024

Eligibility

 Yes No Not Sure

Inclusion Criteria

Any patient over 18 years treated according to the standard of care
Willing to participate in the study by giving an informed consent

Exclusion Criteria

Patients under 18 years of age
Not willing to participate in the study
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